We pair an investigational electrical brain stimulation protocol with the language instruction which learners are already practicing. The outcomes we measure: decoding unfamiliar words, acquiring new vocabulary, and retention after treatment ends.
From the published literature
The findings below describe effects observed in past studies of tES (transcranial electrical stimulation). They are the load-bearing prior work for the research we run.
A 2025 scoping review of every published tES clinical trial in developmental dyslexia found positive effects on reading in all eleven, with the strongest, most consistent signal on novel-word decoding, the core skill at the center of the condition.
In a randomized five-day trial, adults who trained with tES learned up to 40% more novel vocabulary than an unstimulated control. Results persisted after the study ran.
Our mission
Build the evidence that brain stimulation can accelerate language learning, whether it's a child decoding their first words or an adult mastering their fifth.
The science, in plain English
Our devices deliver a small electrical current, roughly the strength of a hearing-aid battery, through two electrodes on the scalp. It isn't strong enough to fire neurons on its own. The tES literature describes the effect as lowering the threshold for firing: the region under the electrode appears to become a little more responsive to whatever it's already trying to do.
Which is why the instruction matters more than the device. We pair the current with active practice (sounding out words, learning new vocabulary) so that the circuits doing that work are engaged at the moment of stimulation. Whether that pairing translates into faster learning, and by how much, is the question each pilot is designed to answer. Stimulation on its own doesn't teach anyone anything.
Different jobs, different targets. For reading and phonics, we target several regions in the system that turns letters into sounds, the network a struggling reader leans on when they meet an unfamiliar word. For language learning, Broca's and Wernicke's areas, the brain's talker and its listener.
Dive into the research
Major studies from the tES (transcranial electrical stimulation) literature in reading and language acquisition.
A 2025 scoping review of the entire tES-for-developmental-dyslexia clinical literature (225 participants total). Strongest, most consistent signal on non-word decoding.
Eighteen sessions of tES paired with phoneme-grapheme training produced low-frequency word and pseudoword reading gains that persisted at six-month follow-up.
In a randomized five-day trial (n=40), adults trained with tES over left temporoparietal cortex learned up to 40% more novel vocabulary than sham controls.
tES over core left-hemisphere language areas facilitated novel word acquisition, with the largest gains for anodal stimulation of Broca's area.
A 2021 systematic review and meta-analysis of tES trials for second- and foreign-language learning in healthy adults: nine studies, 279 participants, moderate overall effect on learning (g=0.50, p=.0001). Biggest gains came when stimulation was applied during the learning phase, not during test.
A meta-analysis of 246 effect sizes from language and math tasks. Stimulation during the learning phase (d=0.712) was more than three times as effective as stimulation during testing (d=0.207), evidence tES drives durable learning, not just an in-the-moment lift.
Eighteen sessions of tDCS paired with cognitive training reduced low-frequency word errors and non-word reading times in children and adolescents with dyslexia. Gains held at one-month follow-up.
Anodal tDCS over left superior temporal gyrus in dyslexic children improved auditory temporal processing, speech-in-noise perception, verbal memory, and reading, with reading improvements statistically tied to the underlying auditory gains.
A crossover trial in 24 children and adolescents with dyslexia: five consecutive daily tDCS sessions produced non-word reading speed gains sustained at one-month follow-up, evidence a short, deployable protocol is enough.
Expert consensus on safe output parameters for transcranial electrical stimulation in wellness, over-the-counter, and consumer applications, the standard our protocol sits inside.
Pilot partners
Golden Advantage Education's team of specialists delivers Orton-Gillingham structured-literacy instruction to students with dyslexia and other learning differences. Jennifer Golden founded the center in 2010; she has been a Certified Orton-Gillingham Specialist since 2003, and is also a Reading Specialist and Special Education Teacher. Golden Advantage is the site of our pediatric reading pilot.
goldenadvantageeducation.com
Jennifer Golden
Founder · Montvale, NJ
The device
Original prototype
The “Citizen Science” Kickstarter Headset.
Next-generation build
A much improved beta NeuroLingo Pro, with adjustable targeting.
In the lab
A beta NeuroLingo Pro in stimulation and comfort testing.
The team
Dr. Alec Sheffield
CEO & Chief Scientific Officer
Yale-trained neuroscientist (PhD, 2025). Expertise in non-invasive brain stimulation and electrophysiology.
Currently learningMandarin Chinese
Luke Knoble
Chief Technology Officer
Ex-Boeing, then to Penumbra building embedded software for stroke-rehabilitation devices. Leads development of the Neurolingo System.
William Polsky
Chief Operations Officer
Mechanical engineer out of the New Haven startup community. Runs design, supply, and manufacturing.
Currently learningItalian
Zida Sung
Principal Electrical Engineer
Specialist in low-power circuit design. Owns the non-invasive brain stimulation circuitry.
Vanacharla Bhaskara
Software Engineering Intern
Master's in Data Science. Machine learning specialist.
Currently learningEsoteric English vocabulary
CZ Martin
Senior Software Engineer
Machine learning specialist and full stack engineer. Virginia Tech, 2019.
Currently learningVietnamese
Advisors
Dr. Joseph Knoble, M.D.
Chief Medical Advisor
Former Chief Fellow at Yale Psychiatry. Clinical safety advisor for the NeuroLingo System.
Jennifer Golden
Curriculum and Assessment Advisor
Certified Orton-Gillingham Specialist since 2003, Author, Reading Specialist, and Special Education Teacher. Founder of Golden Advantage Education.
The company
General Neuroscience designs and manufactures its own transcranial electrical stimulation hardware and runs it under protocols reviewed by WCG. More than 200 people have used the NeuroLingo to date.
Our pilot protocols are reviewed by WCG, an independent institutional review board.
SOSV is our institutional investor. Its hardware program, HAX, helps manufacture our headsets, the same program behind Formlabs, Opentrons, Neurode, Samphire Neuro, and Flow Neuro. We came out of the Tsai Center for Innovative Thinking at Yale (Tsai CITY).
We are enrolling now at Golden Advantage Education, an Orton-Gillingham structured-literacy center in Montvale, New Jersey. Two further sites, a university intensive English program and a research-university neurostimulation lab, will be named as each partner is ready.