General Neuroscience partners with specialty schools, clinics, and tutors serving kids with dyslexia — running co-designed pilots of an evidence-based tES protocol, paired with structured phonics training, that targets the phonological decoding deficit at its core.
Protocol based on 11 published tES (transcranial electrical stimulation) clinical trials in dyslexia — every one improved reading. Pilots run 2–4 weeks with 20+ students ages 8+.
The problem
Evidence-based reading interventions — Orton-Gillingham, Wilson, structured literacy — work. But, it's expensive, time consuming, and too many students end up on the waitlist.
General Neuroscience is building an evidence-based protocol that pairs transcranial electrical stimulation (tES) with structured phonics training. Deployed in short courses at clinics or in schools, it targets exactly the neural system — left parieto-temporal cortex — that the reading-science literature has spent fifteen years mapping.
Who we partner with
Our pilots sit inside the work your program already does — the structured phonics, the reading progress monitoring, the relationships with students and families. Where you administer formal assessments, we map pre/post outcomes onto the instruments you already use.
The evidence base
A 2025 scoping review of the complete tES-for-dyslexia clinical literature found positive effects on reading in every published trial (11 / 11) — with the strongest, most consistent signal on non-word reading, the core phonological decoding skill at the center of the condition.
Children receiving active tES with concurrent reading training show non-word reading speed improvements equivalent to 4–8 years of typical developmental progression.
Non-word reading efficiency remained significantly better than sham at 6-month follow-up — the longest interval tested in the pediatric literature.
Across all published pediatric tES-for-dyslexia studies, only transient scalp tingling in a minority. No cognitive, psychological, or neurological adverse events reported.
How a pilot works
Pilots run 2–4 weeks depending on your setting and cohort size. We handle device logistics, training, study design, and analysis. You keep control of your learning environment and your relationships with families. Our Yale-trained neuroscientist, Dr. Alec Sheffield, stays available throughout.
We meet with your clinical or academic lead to understand your patient population, screening workflow, and timeline. No commitment required.
Baseline measures — age, verbal working memory, phoneme blending, non-word reading — produce a clinical suitability score per child.
Fixed-position tES headsets, structured phonics app, and clinician training. A dedicated support contact is assigned for the entire pilot.
Pre/post and follow-up assessments on standardized non-word reading instruments, analyzed and written up as a co-branded clinical report.
The protocol
Each session pairs 1–4 mA transcranial electrical stimulation (left-anodal / right-cathodal parieto-temporal montage) with the structured phonics work your students are already doing. Parameters sit well inside LOTES-2023 limited-output safety guidance.
Schedule
The partnership
Pilots are offered at cost or below. The goal is clinical evidence and a long-term partnership — not margin on the pilot itself.
What we provide
What we ask from you
Next step
A 30-minute call is enough to figure out whether your patient population, diagnostic workflow, and timeline are a fit. If they aren't, we'll tell you directly.
